Content-type: text/html Man page of GESTIMATOR

GESTIMATOR

Section: User Commands (1)
Updated: April 3, 2002
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NAME

gestimator - The "GNU estimator" (pronounced guesstimator) is a program to calculate divergence between coding sequences  

SYNOPSIS

gestimator -i <infile> [options]  

DESCRIPTION

The primary function of gestimator calculates nonsynonymous (Ka) and synonymous (Ks) distances between DNA sequences, using Comeron's method (Comeron, J. (1995) J. Molecular Evolution, 41: 1152-1159). To keep all the output numeric, the value '999' may be reported if the divergence calculation cannot be made. The program will do all pairwise comparisons for a file containing more than 2 sequences

 

OPTIONS

gestimator accepts the following options:
-i <infile>
specify a file containing aligned sequences in FASTA format to analyze
-v
verbose output. See Comeron's paper for an explanation of the variables.
-m <maxhits>
maxhits is an int referring to the maximum number of differences between two aligned codons to analyze. Accepted values are 1,2, or 3.
-g
remove gaps from the whole aligment before doing any calculations. The default behavior is to remove the gaps from each pairwise comparison.
 

AUTHOR

Kevin Thornton <k-thornton@uchicago.edu>


 

Index

NAME
SYNOPSIS
DESCRIPTION
OPTIONS
AUTHOR

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